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Travis Hafner and Mark DeRosa each hit a two-run homers for the Indians, who avoided their worst start in 95 years. Cleveland lost its first six games in 1914.
The Blue Jays had scored a major league-high 42 runs in winning five of their first six games, but managed only four runs and three hits against the right-hander.
White Sox 6, Twins 1
Jim Thome hit a two-run homer to break open a pitcher's duel, Mark Buehrle was dominant into the seventh inning and the Chicago White Sox won to split a season-opening six-game homestand.
Buehrle (1-0) gave up a solo home run to Delmon Young in the second and then retired 15 straight batters before being pulled with one out in the seventh.
Rays 11, Orioles 3
James Shields pitched seven innings of three-hit ball, Evan Longoria hit his major league-leading fifth home run and visiting Tampa Bay averted a three-game sweep.
Longoria went 3 for 5 to up his average to .481. He has five straight multihit games and at least one RBI in five of his six starts.
Adam Eaton (0-1) allowed four runs and eight hits over four innings in his debut with Baltimore.
Royals 6, Yankees 4
John Buck homered and drove in three runs, helping host Kansas City rally to avoid a three-game sweep.
The Royals scored three runs with two outs in the eighth inning off Jose Veras and Phil Coke (0-1), spoiling a solid start by Joba Chamberlain in his season debut.
Tigers 6, Rangers 4
Brandon Inge homered and hit a two-run single in a six-run eighth inning as the host Tigers rallied to complete a three-game sweep.
Carlos Guillen also had a two-run double for Detroit, which trailed 4-0 after seven innings. Placido Polanco went 3 for 4 with an RBI .
Angels 5, Red Sox 4
Bobby Abreu hit a go-ahead two-run single and Vladimir Guerrero hit his first home run of the season, leading Los Angeles over Boston.
Dustin Moseley (1-0) was charged with three runs and six hits in 5\u2154 innings and struck out three in the finale of a tragic and somber season-opening homestand for the two-time defending AL West champions.
Mariners 1, Athletics 0
Erik Bedard allowed three hits pitching into the ninth inning, and Mike Sweeney's run-scoring double broke up a no-hit bid by Trevor Cahill and gave Seattle a victory on the road.
Bedard (1-0) allowed two hits through the fourth before retiring 13 batters in a row.
Just as good was Cahill (0-1), who retired 11 straight before Adrian Beltre singled up the middle with one out in the seventh.
After Russell Branyan flew out, Sweeney drove in the game's only run with a double to center.
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